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Antikörper

EIF4EBP1 (Ab-69) Antibody

Produktgrößen
100 ul
£332,00
CSB-PA936560-100UL
Über dieses Produkt
SKU:
CSB-PA936560
Zusätzliche Namen:
4E-BP1 antibody; 4EBP1 antibody; 4EBP1_HUMAN antibody; BP 1 antibody; eIF4E binding protein 1 antibody; eIF4E-binding protein 1 antibody; Eif4ebp1 antibody; Eukaryotic translation initiation factor 4E-binding protein 1 antibody; PHAS-I antibody; PHASI antibody; Phosphorylated heat- and acid-stable protein regulated by insulin 1 antibody
Anwendung:
ELISA, Immunohistochemistry, Western Blot
Buffer:
phosphate buffered saline (without mg2+ and ca2+)
Klonalität:
Polyclonal
Weitere Details:
Regulates eIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways. Anne-Claude Gingras, Genes & Dev., Jun 1999; 13: 1422. Guangming Liu, J. Biol. Chem., Mar 2002; 277: 8810 - 8816. Ya-Ping Jiang, J. Biol. Chem., Mar 2001; 276: 10943 - 10951. Anne-Claude Gingras, Genes & Dev., Feb 1998; 12: 502.
Host:
Rabbit
Immunogen:
Synthesized non-phosphopeptide derived from Human 4E-BP1 around the phosphorylation site of threonine 70 (A-K-T-P-P).
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody