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Antikörper

CDK5R1 Antibody

Produktgrößen
100 ul
£332,00
CSB-PA932439-100UL
Über dieses Produkt
SKU:
CSB-PA932439
Zusätzliche Namen:
CD5R1_HUMAN antibody; CDK5 activator 1 antibody; CDK5P35 antibody; CDK5R antibody; CDK5R1 antibody; Cyclin dependent kinase 5 regulatory subunit 1 antibody; Cyclin-dependent kinase 5 activator 1 antibody; Cyclin-dependent kinase 5 regulatory subunit 1 antibody; NCK 5A antibody; Neuronal CDK5 activator antibody; p23 antibody; p25 antibody; p35 antibody; Regulatory partner for CDK5 kinase antibody; Tau protein kinase II 23 kDa subunit antibody; TPKII regulatory subunit antibody
Anwendung:
ELISA, Immunofluorescence, Western Blot
Buffer:
phosphate buffered saline (without mg2+ and ca2+)
Klonalität:
Polyclonal
Weitere Details:
p35 is a neuron specific activator of CDK5. The complex p35/CDK5 is required for neurite outgrowth and cortical lamination. Involved in dendritic spine morphogenesis by mediating the EFNA1-EPHA4 signaling. Activator of TPKII. The complex p35/CDK5 participates in the regulation of the circadian clock by modulating the function of CLOCK protein: phosphorylates CLOCK at 'Thr-451' and 'Thr-461' and regulates the transcriptional activity of the CLOCK-ARNTL/BMAL1 heterodimer in association with altered stability and subcellular distribution. Tsai L.-H., Nature 371:419-423(1994). Patrick G.N., Nature 402:615-622(1999). Kesavapany S., J. Neurosci. 24:4421-4431(2004).
Host:
Rabbit
Immunogen:
Synthesized peptide derived from internal of Human CDK5R1.
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody