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Antikörper

Phospho-BLK (Tyr501) Antibody

Produktgrößen
100 ul
£402,00
CSB-PA928568-100UL
Über dieses Produkt
SKU:
CSB-PA928568
Zusätzliche Namen:
B lymphocyte kinase antibody; B lymphoid tyrosine kinase antibody; Blk antibody; BLK nonreceptor tyrosine kinase antibody; BLK_HUMAN antibody; EC 2.7.10.2 antibody; MGC 10442 antibody; MGC10442 antibody; MODY 11 antibody; MODY11 antibody; P55 BLK antibody; p55-BLK antibody; Tyrosine kinase B lymphocyte specific antibody; Tyrosine protein kinase antibody; Tyrosine-protein kinase BLK antibody
Anwendung:
ELISA, Immunohistochemistry
Buffer:
phosphate buffered saline (without mg2+ and ca2+)
Klonalität:
Polyclonal
Weitere Details:
Non-receptor tyrosine kinase involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulins and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis downstream of B-cell receptor. Islam K.B., J. Immunol. 154:1265-1272(1995). Drebin J.A.,Oncogene 10:477-486(1995). Greenman C.,Nature 446:153-158(2007).
Host:
Rabbit
Immunogen:
Peptide sequence around phosphorylation site of tyrosine 501 (R-Q-Y(p)-E-L) derived from Human BLK.
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody