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Antikörper

GRM4 Antibody

Produktgrößen
50 ul
£186,00
CSB-PA923348-50UL
100 ul
£334,00
CSB-PA923348-100UL
Über dieses Produkt
SKU:
CSB-PA923348
Zusätzliche Namen:
Glutamate receptor metabotropic 4 antibody; GPRC1D antibody; Grm4 antibody; GRM4_HUMAN antibody; Metabotropic glutamate receptor 4 antibody; mGlu4 antibody; mGluR4 antibody
Anwendung:
ELISA, Immunohistochemistry
Buffer:
PBS
Klonalität:
Polyclonal
Weitere Details:
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Several transcript variants encoding different isoforms have been found for this gene.
Host:
Rabbit
Immunogen:
Synthetic peptide of Human GRM4
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody