JUP Antibody
Produktgrößen
100 ul
£332,00
CSB-PA909861-100UL
Über dieses Produkt
- SKU:
- CSB-PA909861
- Zusätzliche Namen:
- ARVD 12 antibody; ARVD12 antibody; Catenin (cadherin associated protein); gamma 80kDa antibody; catenin (cadherin-associated protein) gamma (80kD) antibody; Catenin gamma antibody; CTNNG antibody; Desmoplakin 3 antibody; Desmoplakin III antibody; Desmoplakin-3 antibody; Desmoplakin3 antibody; DesmoplakinIII antibody; DP 3 antibody; DP III antibody; DP3 antibody; DPIII antibody; gamma catenin antibody; Junction plakoglobin antibody; JUP antibody; OTTHUMP00000164732 antibody; OTTHUMP00000164735 antibody; OTTHUMP00000164738 antibody; PDGB antibody; PKGB antibody; PLAK_HUMAN antibody; PLAKOGLOBIN antibody
- Anwendung:
- ELISA, Western Blot
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Klonalität:
- Polyclonal
- Weitere Details:
- Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton "Characterization of the interactions of a-catenin with a-actinin and beta-catenin/plakoglobin." Nieset J.E., Redfield A.R., Jin F., et al. J. Cell Sci. 110:1013-1022(1997) "Interaction of the DF3/MUC1 breast carcinoma-associated antigen and beta-catenin in cell adhesion." Yamamoto M., Bharti A., Li Y., Kufe D. J. Biol. Chem. 272:12492-12494(1997) "The transmembrane receptor protein tyrosine phosphatase DEP1 interacts with p120(ctn)." Holsinger L.J., Ward K., Duffield B., Zachwieja J., Jallal B. Oncogene 21:7067-7076(2002)
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around aa.726~730(I-D-T-Y-S) derived from Human g-Catenin
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:JUP-Antibody-11083363.html
