INO80 Antibody
Produktgrößen
50 ug
£186,00
CSB-PA892466LA01HU-50UG
100 ug
£334,00
CSB-PA892466LA01HU-100UG
Über dieses Produkt
- SKU:
- CSB-PA892466LA01HU
- Zusätzliche Namen:
- DNA helicase INO80 antibody; hINO80 antibody; homolog of yeast INO80 antibody; INO80 antibody; INO80 complex subunit A antibody; INO80 homolog antibody; INO80_HUMAN antibody; INO80A antibody; INOC1 antibody; KIAA1259 antibody; Putative DNA helicase INO80 complex homolog 1 antibody
- Anwendung:
- ELISA, Immunofluorescence, Western Blot
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
- Klonalität:
- Polyclonal
- Weitere Details:
- ATPase component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and DNA repair (PubMed:16230350, PubMed:16298340, PubMed:17721549, PubMed:20855601, PubMed:20237820). Binds DNA (PubMed:16298340, PubMed:21303910). As part of the INO80 complex, remodels chromatin by shifting nucleosomes (PubMed:16230350, PubMed:21303910). Regulates transcription upon recruitment by YY1 to YY1-activated genes, where it acts as an essential coactivator (PubMed:17721549). Involved in UV-damage excision DNA repair (PubMed:20855601). The contribution to DNA double-strand break repair appears to be largely indirect through transcriptional regulation (PubMed:20687897). Involved in DNA replication (PubMed:20237820). Required for microtubule assembly during mitosis thereby regulating chromosome segregation cycle (PubMed:20237820).
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Chromatin-remodeling ATPase INO80 protein (1365-1495AA)
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:INO80-Antibody-12921036.html
