MBNL1 Antibody, Biotin conjugated
Produktgrößen
50 ug
£186,00
CSB-PA889088LD01HU-50UG
100 ug
£334,00
CSB-PA889088LD01HU-100UG
Über dieses Produkt
- SKU:
- CSB-PA889088LD01HU
- Zusätzliche Namen:
- EXP antibody; EXP35 antibody; EXP40 antibody; EXP42 antibody; KIAA0428 antibody; MBNL antibody; MBNL protein antibody; MBNL1 antibody; MBNL1_HUMAN antibody; Muscleblind 41kD isoform antibody; Muscleblind like antibody; Muscleblind like protein 1 antibody; Muscleblind like splicing regulator 1 antibody; Muscleblind-like protein 1 antibody; Triplet expansion RNA binding protein antibody; Triplet-expansion RNA-binding protein antibody
- Anwendung:
- ELISA
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Klonalität:
- Polyclonal
- Konjugat:
- Biotin
- Weitere Details:
- Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. Regulates the TNNT2 exon 5 skipping through competition with U2AF2. Inhibits the formation of the spliceosome A complex on intron 4 of TNNT2 pre-mRNA. Binds to the stem-loop structure within the polypyrimidine tract of TNNT2 intron 4 during spliceosome assembly. Binds to the 5'-YGCU(U/G)Y-3'consensus sequence. Binds to the IR RNA. Binds to expanded CUG repeat RNA, which folds into a hairpin structure containing GC base pairs and bulged, unpaired U residues.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Muscleblind-like protein 1 protein (1-382AA)
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:MBNL1-AntibodyBiotin-conjugated-1029244.html