NUDT15 Antibody, Biotin conjugated
Produktgrößen
50 ug
£186,00
CSB-PA885733LD01HU-50UG
100 ug
£334,00
CSB-PA885733LD01HU-100UG
Über dieses Produkt
- SKU:
- CSB-PA885733LD01HU
- Zusätzliche Namen:
- 8-dihydro-8-oxoguanine triphosphatase NUDT15 antibody; 8-oxo-dGTPase NUDT15 antibody; A730068G11Rik antibody; EC 3.1.6.- antibody; FLJ10956 antibody; MGC104352 antibody; MTH2 antibody; MutT homolog 2 antibody; Nucleoside diphosphate-linked moiety X motif 15 antibody; NUD15_HUMAN antibody; Nudix (nucleoside diphosphate linked moiety X)-type motif antibody; Nudix motif 15 antibody; NUDT15 antibody; OTTHUMP00000018389 antibody; Probable 7 antibody; Probable 7,8-dihydro-8-oxoguanine triphosphatase NUDT15 antibody; RP11-90M2.1 antibody
- Anwendung:
- ELISA
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
- Klonalität:
- Polyclonal
- Konjugat:
- Biotin
- Weitere Details:
- May catalyze the hydrolysis of nucleoside triphosphates including dGTP, dTTP, dCTP, their oxidized forms like 8-oxo-dGTP and the prodrug thiopurine derivatives 6-thio-dGTP and 6-thio-GTP (PubMed:26238318). Could also catalyze the hydrolysis of some nucleoside diphosphate derivatives (PubMed:22556419, PubMed:26238318). Hydrolyzes oxidized nucleosides triphosphates like 8-oxo-dGTP in vitro, but the specificity and efficiency towards these substrates are low. Therefore, the potential in vivo sanitizing role of this enzyme, that would consist in removing oxidatively damaged forms of nucleosides to prevent their incorporation into DNA, is unclear (PubMed:26238318, PubMed:22556419). Through the hydrolysis of thioguanosine triphosphates may participate in the catabolism of thiopurine drugs (PubMed:26238318, PubMed:25108385). May also have a role in DNA synthesis and cell cycle progression by stabilizing PCNA (PubMed:19419956).
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Nucleotide triphosphate diphosphatase NUDT15 protein (1-164AA)
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:NUDT15-AntibodyBiotin-conjugated-12557088.html