CISH Antibody

Produktgrößen

50 ul

£186,00

CSB-PA885721ESR1HU-50UL

100 ul

£334,00

CSB-PA885721ESR1HU-100UL

Über dieses Produkt

SKU:: CSB-PA885721ESR1HU
Zusätzliche Namen:: BACTS2 antibody; cis 1 antibody; CIS antibody; CIS-1 antibody; CIS1 antibody; Cish antibody; CISH_HUMAN antibody; Cytokine inducible inhibitor of signaling type 1B antibody; Cytokine inducible SH2 containing protein antibody; Cytokine-inducible SH2-containing protein antibody; G18 antibody; Protein G18 antibody; SOCS antibody; Suppressor of cytokine signaling antibody
Anwendung:: ELISA, Immunohistochemistry
Buffer:: PBS
Klonalität:: Polyclonal
Weitere Details:: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. CIS is involved in the negative regulation of cytokines that signal through the JAK-STAT5 pathway such as erythropoietin, prolactin and interleukin 3 (IL3) receptor. Inhibits STAT5 trans-activation by suppressing its tyrosine phosphorylation. May be a substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Host:: Rabbit
Immunogen:: Recombinant Human Cytokine-inducible SH2-containing protein (1-257AA)
Isotyp:: IgG
Physischer Zustand:: Liquid
Aufreinigung:: Affinity Purified
Reaktivitäten:: Human
Versandbedingungen:: Blue Ice
Lagerbedingungen:: -20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:: Cusabio
Typ:: Antibody: Polyclonal Antibody

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