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Antikörper

BACH2 Antibody

Produktgrößen
50 ug
£186,00
CSB-PA883639LA01HU-50UG
100 ug
£334,00
CSB-PA883639LA01HU-100UG
Über dieses Produkt
SKU:
CSB-PA883639LA01HU
Zusätzliche Namen:
Bach 2 antibody; Bach2 antibody; BACH2_HUMAN antibody; Basic leucine zipper transcription factor 2 antibody; BTB and CNC homolog 2 antibody; BTB and CNC homology 1 basic leucine zipper transcription factor 2 antibody; BTB domain and CNC homolog 2 antibody; BTBD25 antibody; OTTHUMP00000016867 antibody; OTTHUMP00000016868 antibody; OTTHUMP00000040591 antibody; Transcription regulator protein BACH2 antibody
Anwendung:
ELISA, Immunofluorescence, Immunohistochemistry
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Klonalität:
Polyclonal
Weitere Details:
Transcriptional regulator that acts as repressor or activator (By similarity). Binds to Maf recognition elements (MARE) (By similarity). Plays an important role in coordinating transcription activation and repression by MAFK (By similarity). Induces apoptosis in response to oxidative stress through repression of the antiapoptotic factor HMOX1 (PubMed:17018862). Positively regulates the nuclear import of actin (By similarity).
Host:
Rabbit
Immunogen:
Recombinant Human Transcription regulator protein BACH2 protein (136-235AA)
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Protein G Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody
Immunofluorescence staining of SH-SY5Y cells with CSB-PA883639LA01HU at 1:66, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
IHC image of CSB-PA883639LA01HU diluted at 1:200 and staining in paraffin-embedded human appendix tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.