HERC5 Antibody, Biotin conjugated
Produktgrößen
50 ug
£186,00
CSB-PA883435LD01HU-50UG
100 ug
£334,00
CSB-PA883435LD01HU-100UG
Über dieses Produkt
- SKU:
- CSB-PA883435LD01HU
- Zusätzliche Namen:
- CEB1 antibody; CEBP1 antibody; Cyclin E binding protein 1 antibody; Cyclin-E-binding protein 1 antibody; E3 ISG15--protein ligase HERC5 antibody; HECT domain and RCC1 like domain containing protein 5 antibody; HECT domain and RCC1-like domain-containing protein 5 antibody; Hect domain and RLD 5 antibody; HECT E3 ubiquitin ligase antibody; HERC5 antibody; HERC5_HUMAN antibody; Herc6 antibody
- Anwendung:
- ELISA
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
- Klonalität:
- Polyclonal
- Konjugat:
- Biotin
- Weitere Details:
- Major E3 ligase for ISG15 conjugation. Acts as a positive regulator of innate antiviral response in cells induced by interferon. Functions as part of the ISGylation machinery that recognizes target proteins in a broad and relatively non-specific manner. Catalyzes ISGylation of IRF3 which results in sustained activation, it attenuates IRF3-PIN1 interaction, which antagonizes IRF3 ubiquitination and degradation, and boosts the antiviral response. Catalyzes ISGylation of influenza A viral NS1 which attenuates virulence; ISGylated NS1 fails to form homodimers and thus to interact with its RNA targets. Catalyzes ISGylation of papillomavirus type 16 L1 protein which results in dominant-negative effect on virus infectivity. Physically associated with polyribosomes, broadly modifies newly synthesized proteins in a cotranslational manner. In an interferon-stimulated cell, newly translated viral proteins are primary targets of ISG15.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human E3 ISG15--protein ligase HERC5 protein (153-284AA)
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:HERC5-Antibody-Biotin-conjugated-12920072.html