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Antikörper

NECTIN3 Antibody

Produktgrößen
50 ul
£186,00
CSB-PA882076ESR2HU-50UL
100 ul
£334,00
CSB-PA882076ESR2HU-100UL
Über dieses Produkt
SKU:
CSB-PA882076ESR2HU
Zusätzliche Namen:
CD113 antibody; CDw113 antibody; DKFZP566B0846 antibody; FLJ90624 antibody; Nectin-3 antibody; Nectin3 antibody; Poliovirus receptor related 3 antibody; Poliovirus receptor related protein 3 antibody; Poliovirus receptor-like 3 antibody; Poliovirus receptor-related protein 3 antibody; PPR3 antibody; PRR3 antibody; Pvrl3 antibody; PVRL3_HUMAN antibody; PVRR3 antibody
Anwendung:
ELISA, Immunohistochemistry
Buffer:
PBS
Klonalität:
Polyclonal
Weitere Details:
Plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins, such as trans-interaction with NECTIN2 at Sertoli-spermatid junctions. Trans-interaction with PVR induces activation of CDC42 and RAC small G proteins through common signaling molecules such as SRC and RAP1. Also involved in the formation of cell-cell junctions, including adherens junctions and synapses. Induces endocytosis-mediated down-regulation of PVR from the cell surface, resulting in reduction of cell movement and proliferation. Plays a role in the morphology of the ciliary body.
Host:
Rabbit
Immunogen:
Recombinant Human Nectin-3 protein (310-549AA)
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody