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Antikörper

CALCOCO1 Antibody

Produktgrößen
50 ul
£186,00
CSB-PA878956ESR1HU-50UL
100 ul
£334,00
CSB-PA878956ESR1HU-100UL
Über dieses Produkt
SKU:
CSB-PA878956ESR1HU
Zusätzliche Namen:
CALCOCO1 antibody; KIAA1536 antibody; PP13275 antibody; UNQ2436/PRO4996Calcium-binding and coiled-coil domain-containing protein 1 antibody; Calphoglin antibody; Coiled-coil coactivator protein antibody; Sarcoma antigen NY-SAR-3 antibody
Anwendung:
ELISA, Immunohistochemistry, Western Blot
Buffer:
PBS
Klonalität:
Polyclonal
Weitere Details:
Functions as a coactivator for aryl hydrocarbon and nuclear receptors (NR). Recruited to promoters through its contact with the N-terminal basic helix-loop-helix-Per-Arnt-Sim (PAS) domain of transcription factors or coactivators, such as NCOA2. During ER-activation acts synergistically in combination with other NCOA2-binding proteins, such as EP300, CREBBP and CARM1. Involved in the transcriptional activation of target genes in the Wnt/CTNNB1 pathway. Functions as a secondary coactivator in LEF1-mediated transcriptional activation via its interaction with CTNNB1. Coactivator function for nuclear receptors and LEF1/CTNNB1 involves differential utilization of two different activation regions (By similarity). In association with CCAR1 enhances GATA1- and MED1-mediated transcriptional activation from the gamma-globin promoter during erythroid differentiation of K562 erythroleukemia cells (PubMed:24245781).
Host:
Rabbit
Immunogen:
Recombinant Human Calcium-binding and coiled-coil domain-containing protein 1 protein (462-691AA)
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody