IL1RAP Antibody
Produktgrößen
50 ul
£186,00
CSB-PA878844ESR1HU-50UL
100 ul
£334,00
CSB-PA878844ESR1HU-100UL
Über dieses Produkt
- SKU:
- CSB-PA878844ESR1HU
- Zusätzliche Namen:
- C3orf13 antibody; FLJ37788 antibody; IL 1 receptor accessory protein antibody; IL 1R 3 antibody; IL 1R3 antibody; IL 1RAcP antibody; IL 1RAP antibody; IL-1 receptor accessory protein antibody; IL-1R-3 antibody; IL-1R3 antibody; IL-1RAcP antibody; IL-1RAP antibody; IL1 receptor accessory protein antibody; IL1AP_HUMAN antibody; IL1R3 antibody; IL1RAcP antibody; Il1rap antibody; Interleukin 1 Accessory Protein antibody; interleukin 1 receptor 3 antibody; Interleukin 1 receptor accessory protein antibody; interleukin 1 receptor accessory protein beta antibody; Interleukin-1 receptor 3 antibody; Interleukin-1 receptor accessory protein antibody
- Anwendung:
- ELISA, Immunohistochemistry
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Weitere Details:
- Coreceptor for IL1RL2 in the IL-36 signaling system (By similarity). Coreceptor with IL1R1 in the IL-1 signaling system. Associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Recruits TOLLIP to the signaling complex. Does not bind to interleukin-1 alone; binding of IL1RN to IL1R1, prevents its association with IL1R1 to form a signaling complex. The cellular response is modulated through a non-signaling association with the membrane IL1R2 decoy receptor. Secreted forms (isoforms 2 and 3) associate with secreted ligand-bound IL1R2 and increase the affinity of secreted IL1R2 for IL1B; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Interleukin-1 receptor accessory protein (21-356AA)
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:IL1RAP-Antibody-11081097.html
