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Antikörper

MARK1 Antibody

Produktgrößen
50 ul
£186,00
CSB-PA873719DSR1HU-50UL
100 ul
£334,00
CSB-PA873719DSR1HU-100UL
Über dieses Produkt
SKU:
CSB-PA873719DSR1HU
Zusätzliche Namen:
KIAA1477 antibody; MAP/microtubule affinity regulating kinase 1 antibody; MAP/microtubule affinity-regulating kinase 1 antibody; MARK 1 antibody; MARK antibody; Mark1 antibody; MARK1_HUMAN antibody; MGC126512 antibody; MGC126513 antibody; Serine/threonine protein kinase MARK1 antibody; Serine/threonine-protein kinase MARK1 antibody
Anwendung:
ELISA, Immunohistochemistry, Western Blot
Buffer:
PBS
Klonalität:
Polyclonal
Weitere Details:
Serine/threonine-protein kinase involved in cell polarity and microtubule dynamics regulation. Phosphorylates DCX, MAP2, MAP4 and MAPT/TAU. Involved in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity and microtubule dynamics, possibly by phosphorylating and regulating DCX. Also acts as a positive regulator of the Wnt signaling pathway, probably by mediating phosphorylation of dishevelled proteins (DVL1, DVL2 and/or DVL3).
Host:
Rabbit
Immunogen:
Recombinant Human Serine/threonine-protein kinase MARK1 protein (560-700AA)
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody