COPS7B Antibody, Biotin conjugated
Produktgrößen
50 ug
£186,00
CSB-PA872526LD01HU-50UG
100 ug
£334,00
CSB-PA872526LD01HU-100UG
Über dieses Produkt
- SKU:
- CSB-PA872526LD01HU
- Zusätzliche Namen:
- COP9 Complex Homolog Subunit 7b antibody; COP9 Constitutive Photomorphogenic Homolog Subunit 7b antibody; COP9 Signalasome Subunit 7b antibody; COP9 signalosome complex subunit 7b antibody; COPS7B antibody; CSN7B_HUMAN antibody; JAB1 Containing Signalosome Subunit 7b antibody; JAB1-containing signalosome subunit 7b antibody; SGN7b antibody; Signalosome subunit 7b antibody
- Anwendung:
- ELISA
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Klonalität:
- Polyclonal
- Konjugat:
- Biotin
- Weitere Details:
- Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human COP9 signalosome complex subunit 7b protein (1-157AA)
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:COPS7B-AntibodyBiotin-conjugated-11116248.html