PINK1 Antibody, FITC conjugated
Produktgrößen
50 ug
£186,00
CSB-PA863144LC01HU-50UG
100 ug
£334,00
CSB-PA863144LC01HU-100UG
Über dieses Produkt
- SKU:
- CSB-PA863144LC01HU
- Zusätzliche Namen:
- BRPK antibody; FLJ27236 antibody; mitochondrial antibody; PARK 6 antibody; PARK6 antibody; Phosphatase and Tensin Homolog antibody; PINK 1 antibody; PINK1 antibody; PINK1_HUMAN antibody; Protein kinase BRPK antibody; PTEN induced putative kinase 1 antibody; PTEN induced putative kinase protein 1 antibody; PTEN-induced putative kinase protein 1 antibody; Serine/threonine kinase PINK1 mitochondrial antibody; Serine/threonine protein kinase PINK1 mitochondrial antibody; Serine/threonine-protein kinase PINK1 antibody
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Klonalität:
- Polyclonal
- Konjugat:
- FITC
- Weitere Details:
- Protects against mitochondrial dysfunction during cellular stress by phosphorylating mitochondrial proteins. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy) by mediating activation and translocation of PARK2. Targets PARK2 to dysfunctional depolarized mitochondria through the phosphorylation of MFN2. Activates PARK2 in 2 steps: (1) by mediating phosphorylation at 'Ser-65' of PARK2 and (2) mediating phosphorylation of ubiquitin, converting PARK2 to its fully-active form (PubMed:24660806, PubMed:24751536, PubMed:24784582, PubMed:25527291).
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Serine/threonine-protein kinase PINK1, mitochondrial protein (162-272AA)
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:PINK1-AntibodyFITC-conjugated-12548735.html