ELF4 Antibody

Produktgrößen

50 ul

£186,00

CSB-PA857453ESR2HU-50UL

100 ul

£334,00

CSB-PA857453ESR2HU-100UL

Über dieses Produkt

SKU:: CSB-PA857453ESR2HU
Zusätzliche Namen:: E74-like factor 4 antibody; ELF4 antibody; ELF4_HUMAN antibody; ELFR antibody; ETS-related transcription factor Elf-4 antibody; ETS-related transcription factor Elf4 antibody; MEF antibody; Myeloid Elf-1-like factor antibody; Myeloid Elf1-like factor antibody
Anwendung:: ELISA, Immunohistochemistry
Buffer:: PBS
Klonalität:: Polyclonal
Weitere Details:: Transcriptional activator that binds to DNA sequences containing the consensus 5'-WGGA-3'. Transactivates promoters of the hematopoietic growth factor genes CSF2, IL3, IL8, and of the bovine lysozyme gene. Acts synergistically with RUNX1 to transactivate the IL3 promoter (By similarity). Also transactivates the PRF1 promoter in natural killer (NK) cells. Plays a role in the development and function of NK and NK T-cells and in innate immunity. Controls the proliferation and homing of CD8+ T-cells via the Kruppel-like factors KLF4 and KLF2 (By similarity). Controls cell senescence in a p53-dependent manner. Can also promote cellular transformation through inhibition of the p16 pathway.
Host:: Rabbit
Immunogen:: Recombinant Human ETS-related transcription factor Elf-4 protein (1-200AA)
Isotyp:: IgG
Physischer Zustand:: Liquid
Aufreinigung:: Affinity Purified
Reaktivitäten:: Human
Versandbedingungen:: Blue Ice
Lagerbedingungen:: -20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:: Cusabio
Typ:: Antibody: Polyclonal Antibody

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