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Antikörper

FERMT2 Antibody, Biotin conjugated

Produktgrößen
50 ug
£186,00
CSB-PA853382LD01HU-50UG
100 ug
£334,00
CSB-PA853382LD01HU-100UG
Über dieses Produkt
SKU:
CSB-PA853382LD01HU
Zusätzliche Namen:
FLJ34213 antibody; FLJ44462 antibody; UNC112 antibody; FERM2_HUMAN antibody; Fermitin family homolog 2 antibody; Fermt2 antibody; KIND2 antibody; Kindlin-2 antibody; MIG-2 antibody; MIG2 antibody; Mitogen-inducible gene 2 protein antibody; PH domain-containing family C member 1 antibody; Pleckstrin homology domain containing family C (with FERM domain) member 1 antibody; Pleckstrin homology domain-containing family C member 1 antibody; PLEKHC1 antibody; UNC112B antibody
Anwendung:
ELISA
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Klonalität:
Polyclonal
Konjugat:
Biotin
Weitere Details:
Scaffolding protein that enhances integrin activation mediated by TLN1 and/or TLN2, but activates integrins only weakly by itself. Binds to membranes enriched in phosphoinositides. Enhances integrin-mediated cell adhesion onto the extracellular matrix and cell spreading; this requires both its ability to interact with integrins and with phospholipid membranes. Required for the assembly of focal adhesions. Participates in the connection between extracellular matrix adhesion sites and the actin cytoskeleton and also in the orchestration of actin assembly and cell shape modulation. Recruits FBLIM1 to focal adhesions. Plays a role in the TGFB1 and integrin signaling pathways. Stabilizes active CTNNB1 and plays a role in the regulation of transcription mediated by CTNNB1 and TCF7L2/TCF4 and in Wnt signaling.
Host:
Rabbit
Immunogen:
Recombinant Human Fermitin family homolog 2 protein (155-232AA)
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Protein G Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody