EZH1 Antibody

Produktgrößen

50 ul

£186,00

CSB-PA852913DSR1HU-50UL

100 ul

£334,00

CSB-PA852913DSR1HU-100UL

Über dieses Produkt

SKU:: CSB-PA852913DSR1HU
Zusätzliche Namen:: Enhancer of zeste homolog 1 (Drosophila) antibody; Enhancer of zeste homolog 1 antibody; ENX-2 antibody; ENX2 antibody; Ezh1 antibody; EZH1_HUMAN antibody; Histone-lysine N-methyltransferase EZH1 antibody
Anwendung:: ELISA, Immunohistochemistry
Buffer:: PBS
Klonalität:: Polyclonal
Weitere Details:: Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, suggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH2-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation.
Host:: Rabbit
Immunogen:: Recombinant Human Histone-lysine N-methyltransferase EZH1 protein (160-280AA)
Isotyp:: IgG
Physischer Zustand:: Liquid
Aufreinigung:: Affinity Purified
Reaktivitäten:: Human
Versandbedingungen:: Blue Ice
Lagerbedingungen:: -20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:: Cusabio
Typ:: Antibody: Polyclonal Antibody

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