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Antikörper

LILRB1 Antibody

Produktgrößen
50 ug
£186,00
CSB-PA847747LA01HU-50UG
100 ug
£334,00
CSB-PA847747LA01HU-100UG
Über dieses Produkt
SKU:
CSB-PA847747LA01HU
Zusätzliche Namen:
CD85 antibody; CD85 antigen antibody; CD85 antigen like family member J antibody; CD85 antigen-like family member J antibody; CD85j antibody; CD85j antigen antibody; Ig like transcript 2 antibody; ILT 2 antibody; ILT-2 antibody; ILT2 antibody; immunoglobulin like transcript 2 antibody; Immunoglobulin-like transcript 2 antibody; leukocyte Ig like receptor 1 antibody; Leukocyte immunoglobulin like receptor 1 antibody; leukocyte immunoglobulin like receptor subfamily B member 1 antibody; Leukocyte immunoglobulin like receptor subfamily B member 1 precursor antibody; leukocyte immunoglobulin like receptor subfamily B member 1 soluble isoform antibody; leukocyte immunoglobulin like receptor, subfamily B, member 1 antibody; Leukocyte immunoglobulin-like receptor 1 antibody; Leukocyte immunoglobulin-like receptor subfamily B member 1 antibody; leukocyte immunoglobulin-like receptor subfamily B member 1 soluble isoform antibody; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 antibody; LILRB1 antibody; LIR 1 antibody; LIR-1 antibody; LIR1 antibody; LIRB1_HUMAN antibody; MIR 7 antibody; MIR-7 antibody; MIR7 antibody; Monocyte/macrophage immunoglobulin like receptor 7 antibody; Monocyte/macrophage immunoglobulin-like receptor 7 antibody; PIR B antibody; PIRB antibody
Anwendung:
ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Klonalität:
Polyclonal
Weitere Details:
Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Receptor for H301/UL18, a human cytomegalovirus class I MHC homolog. Ligand binding results in inhibitory signals and down-regulation of the immune response. Engagement of LILRB1 present on natural killer cells or T-cells by class I MHC molecules protects the target cells from lysis. Interaction with HLA-B or HLA-E leads to inhibition of the signal triggered by FCER1A and inhibits serotonin release. Inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.
Host:
Rabbit
Immunogen:
Recombinant Human Leukocyte immunoglobulin-like receptor subfamily B member 1 protein (483-650AA)
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Protein G Purified
Reaktivitäten:
Human, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody
Immunofluorescence staining of 293 cells with CSB-PA847747LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
IHC image of CSB-PA847747LA01HU diluted at 1:400 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Western Blot Positive WB detected in: THP-1 whole cell lysate, Rat brain tissue All lanes: LILRB1 antibody at 3.5ug/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 71, 72, 50 kDa Observed band size: 71 kDa