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Antikörper

HORMAD2 Antibody, FITC conjugated

Produktgrößen
50 ug
£186,00
CSB-PA836683LC01HU-50UG
100 ug
£334,00
CSB-PA836683LC01HU-100UG
Über dieses Produkt
SKU:
CSB-PA836683LC01HU
Zusätzliche Namen:
4930529M09Rik antibody; CT46.2 antibody; HORM2_HUMAN antibody; HORMA domain containing 2 antibody; HORMA domain-containing protein 2 antibody; Hormad2 antibody; MGC26710 antibody; RP23-329P17.4 antibody
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Klonalität:
Polyclonal
Konjugat:
FITC
Weitere Details:
Essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes. Required for the DNA double-strand break-independent, BRCA1-dependent activation of ATR on the sex chromosomes that is essential for normal sex body formation.
Host:
Rabbit
Immunogen:
Recombinant Human HORMA domain-containing protein 2 protein (14-307AA)
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Protein G Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody