DOCK7 Antibody
Produktgrößen
50 ug
£186,00
CSB-PA836266LA01HU-50UG
100 ug
£334,00
CSB-PA836266LA01HU-100UG
Über dieses Produkt
- SKU:
- CSB-PA836266LA01HU
- Zusätzliche Namen:
- DOCK7 antibody; KIAA1771Dedicator of cytokinesis protein 7 antibody
- Anwendung:
- ELISA, Immunofluorescence, Western Blot
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Klonalität:
- Polyclonal
- Weitere Details:
- Functions as a guanine nucleotide exchange factor (GEF), which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. Does not have a GEF activity for CDC42. Required for STMN1 'Ser-15' phosphorylation during axon formation and consequently for neuronal polarization (PubMed:16982419). Has a role in pigmentation (By similarity). Involved in the regulation of cortical neurogenesis through the control of radial glial cells (RGCs) proliferation versus differentiation; negatively regulates the basal-to-apical interkinetic nuclear migration of RGCs by antagonizing the microtubule growth-promoting function of TACC3 (By similarity).
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Dedicator of cytokinesis protein 7 protein (1440-1671AA)
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:DOCK7-Antibody-12548654.html
