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Antikörper

DPF1 Antibody

Produktgrößen
50 ul
£186,00
CSB-PA835697ESR1HU-50UL
100 ul
£334,00
CSB-PA835697ESR1HU-100UL
Über dieses Produkt
SKU:
CSB-PA835697ESR1HU
Zusätzliche Namen:
BAF45B antibody; BRG1-associated factor 45B antibody; D4 antibody; D4 zinc and double PHD fingers family 1 antibody; DPF1 antibody; DPF1_HUMAN antibody; NEUD4 antibody; Neuro d4 homolog antibody; Zinc and double PHD fingers family 1 antibody; Zinc finger protein neuro-d4 antibody
Anwendung:
ELISA, Immunohistochemistry
Buffer:
PBS
Klonalität:
Polyclonal
Weitere Details:
May have an important role in developing neurons by participating in regulation of cell survival, possibly as a neurospecific transcription factor. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity).
Host:
Rabbit
Immunogen:
Recombinant Human Zinc finger protein neuro-d4 protein (261-380AA)
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody