HTRA1 Antibody, FITC conjugated
Produktgrößen
50 ul
£186,00
CSB-PA835695LC01HU-50UL
100 ul
£334,00
CSB-PA835695LC01HU-100UL
Über dieses Produkt
- SKU:
- CSB-PA835695LC01HU
- Zusätzliche Namen:
- ARMD7 antibody; CARASIL antibody; High-temperature requirement A serine peptidase 1 antibody; HtrA antibody; HtrA serine peptidase 1 antibody; HTRA1 antibody; HTRA1_HUMAN antibody; IGFBP5 protease antibody; L56 antibody; ORF480 antibody; Protease serine 11 (IGF binding) antibody; protease serine 11 antibody; PRSS11 antibody; Serine protease 11 antibody; Serine protease HTRA1 antibody; Serine protease HTRA1 precursor antibody
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
- Klonalität:
- Polyclonal
- Konjugat:
- FITC
- Weitere Details:
- Serine protease with a variety of targets, including extracellular matrix proteins such as fibronectin. HTRA1-generated fibronectin fragments further induce synovial cells to up-regulate MMP1 and MMP3 production. May also degrade proteoglycans, such as aggrecan, decorin and fibromodulin. Through cleavage of proteoglycans, may release soluble FGF-glycosaminoglycan complexes that promote the range and intensity of FGF signals in the extracellular space. Regulates the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. Inhibits signaling mediated by TGF-beta family members. This activity requires the integrity of the catalytic site, although it is unclear whether TGF-beta proteins are themselves degraded. By acting on TGF-beta signaling, may regulate many physiological processes, including retinal angiogenesis and neuronal survival and maturation during development. Intracellularly, degrades TSC2, leading to the activation of TSC2 downstream targets.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Serine protease HTRA1 protein (23-248AA)
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:HTRA1-Antibody--FITC-conjugated-12926866.html