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Antikörper

BAX (Ab-167) Antibody

Produktgrößen
100 ul
£332,00
CSB-PA834415-100UL
Über dieses Produkt
SKU:
CSB-PA834415
Zusätzliche Namen:
Apoptosis regulator BAX antibody; BAX antibody; Bax-protein antibody; BAX_HUMAN antibody; BAXA antibody; Baxdelta2G9 antibody; Baxdelta2G9omega antibody; Baxdelta2omega antibody; Bcl-2-like protein 4 antibody; BCL2 associated X protein antibody; BCL2 associated X protein omega antibody; BCL2 associated X protein transcript variant delta2 antibody; Bcl2-L-4 antibody; BCL2L4 antibody; membrane isoform alpha antibody
Anwendung:
ELISA, Immunofluorescence, Western Blot
Buffer:
phosphate buffered saline (without mg2+ and ca2+)
Klonalität:
Polyclonal
Weitere Details:
Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis. Oltvai Z.N., Cell 74:609-619(1993). Cuddeback S.M., J. Biol. Chem. 276:20559-20565(2001). Guo B., Nature 423:456-461(2003)
Host:
Rabbit
Immunogen:
Synthesized non-phosphopeptide derived from Human Bax around the phosphorylation site of threonine 167 (F-G-T(p)-P-T).
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody