Histone H2AX Antibody
Produktgrößen
100 ul
£332,00
CSB-PA833019-100UL
Über dieses Produkt
- SKU:
- CSB-PA833019
- Zusätzliche Namen:
- H2A histone family member X antibody; H2A histone family member X antibody; H2A.FX antibody; H2A.X antibody; H2a/x antibody; H2AFX antibody; H2AX antibody; H2AX_HUMAN antibody; Histone H2A.X antibody
- Anwendung:
- ELISA, Immunofluorescence, Western Blot
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Klonalität:
- Polyclonal
- Weitere Details:
- Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation. The MGC Project Team; Genome Res. 14:2121-2127(2004). Rogakou E.P., J. Biol. Chem. 273:5858-5868(1998). Rogakou E.P., J. Biol. Chem. 275:9390-9395(2000).
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from internal of Human Histone H2AX.
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:Histone-H2AX-Antibody-11084867.html
