HDAC9 Antibody
Produktgrößen
100 ul
£332,00
CSB-PA831141-100UL
Über dieses Produkt
- SKU:
- CSB-PA831141
- Zusätzliche Namen:
- HD 7 antibody; HD 7B antibody; HD 9 antibody; HD7 antibody; HD7B antibody; HD9 antibody; HDAC 7 antibody; HDAC 7B antibody; HDAC 9 antibody; HDAC 9B antibody; HDAC 9FL antibody; HDAC antibody; HDAC7 antibody; HDAC7B antibody; HDAC9 antibody; HDAC9_HUMAN antibody; HDAC9B antibody; HDAC9FL antibody; HDRP antibody; Histone deacetylase 4/5 related protein antibody; Histone deacetylase 7 antibody; Histone deacetylase 7B antibody; Histone deacetylase 9 antibody; Histone deacetylase 9A antibody; Histone deacetylase related protein antibody; Histone deacetylase-related protein antibody; KIAA0744 antibody; MEF2 interacting transcription repressor MITR antibody; MEF2 interacting transcription repressor protein antibody; MEF2-interacting transcription repressor MITR antibody; MITR antibody
- Anwendung:
- ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Klonalität:
- Polyclonal
- Weitere Details:
- Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Represses MEF2-dependent transcription. Isoform 3 lacks active site residues and therefore is catalytically inactive. Represses MEF2-dependent transcription by recruiting HDAC1 and/or HDAC3. Seems to inhibit skeletal myogenesis and to be involved in heart development. Protects neurons from apoptosis, both by inhibiting JUN phosphorylation by MAPK10 and by repressing JUN transcription via HDAC1 recruitment to JUN promoter. Michael Haberland, Mol. Cell. Biol., Jan 2007; 27: 518 - 525. Xianbo Zhou, PNAS, Sep 2001; 98: 10572. Kevin Petrie, J. Biol. Chem., Apr 2003; 278: 16059 - 16072. Kevin Petrie, Blood (ASH Annual Meeting Abstracts), Nov 2004; 104: 1120.
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from Human HDAC9.
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:HDAC9-Antibody-11084577.html
