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Antikörper

GEMIN6 Antibody, HRP conjugated

Produktgrößen
50 ug
£186,00
CSB-PA823902LB01HU-50UG
100 ug
£334,00
CSB-PA823902LB01HU-100UG
Über dieses Produkt
SKU:
CSB-PA823902LB01HU
Zusätzliche Namen:
FLJ23459 antibody; Gem (nuclear organelle) associated protein 6 antibody; Gem-associated protein 6 antibody; GEMI6 antibody; GEMI6_HUMAN antibody; Gemin 6 antibody; Gemin-6 antibody; Gemin6 antibody; SIP2 antibody
Anwendung:
ELISA
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Klonalität:
Polyclonal
Konjugat:
HRP
Weitere Details:
The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus.
Host:
Rabbit
Immunogen:
Recombinant Human Gem-associated protein 6 protein (1-167AA)
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Protein G Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody