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Antikörper

PRIMPOL Antibody, HRP conjugated

Produktgrößen
50 ug
£186,00
CSB-PA822255LB01HU-50UG
100 ug
£334,00
CSB-PA822255LB01HU-100UG
Über dieses Produkt
SKU:
CSB-PA822255LB01HU
Zusätzliche Namen:
CC111_HUMAN antibody; CCDC111 antibody; Coiled coil domain containing 111 antibody; Coiled-coil domain-containing protein 111 antibody; DNA-directed primase/polymerase protein antibody; MYP22 antibody; Primase and polymerase (DNA directed) antibody; PRIMPOL antibody
Anwendung:
ELISA
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Klonalität:
Polyclonal
Konjugat:
HRP
Weitere Details:
DNA primase and DNA polymerase able to initiate de novo DNA synthesis using dNTPs. Shows a high capacity to tolerate DNA damage lesions such as 8oxoG and abasic sites in DNA. Involved in translesion synthesis via its primase activity by mediating uninterrupted fork progression after programmed or damage-induced fork arrest and by reinitiating DNA synthesis after dNTP depletion. Required for mitochondrial DNA (mtDNA) synthesis, suggesting it may be involved in DNA tolerance during the replication of mitochondrial DNA. Has non-overlapping function with POLH.
Host:
Rabbit
Immunogen:
Recombinant Human DNA-directed primase/polymerase protein (305-537AA)
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Protein G Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody