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Antikörper

IFNL1 Antibody

Produktgrößen
50 ul
£186,00
CSB-PA811596ESR2HU-50UL
100 ul
£334,00
CSB-PA811596ESR2HU-100UL
Über dieses Produkt
SKU:
CSB-PA811596ESR2HU
Zusätzliche Namen:
IFNL1 antibody; IL29 antibody; ZCYTO21Interferon lambda-1 antibody; IFN-lambda-1 antibody; Cytokine Zcyto21 antibody; Interleukin-29 antibody; IL-29 antibody
Anwendung:
ELISA, Immunohistochemistry
Buffer:
PBS
Klonalität:
Polyclonal
Weitere Details:
Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.
Host:
Rabbit
Immunogen:
Recombinant Human Interferon lambda-1 protein (20-200AA)
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody