Phospho-CAD (Thr456) Antibody
Produktgrößen
100 ul
£402,00
CSB-PA793920-100UL
Über dieses Produkt
- SKU:
- CSB-PA793920
- Zusätzliche Namen:
- CAD antibody; CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase antibody; EC 6.3.5.5); Aspartate carbamoyltransferase antibody; EC 2.1.3.2); Dihydroorotase antibody; EC 3.5.2.3)] antibody
- Anwendung:
- ELISA, Immunohistochemistry
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Klonalität:
- Polyclonal
- Weitere Details:
- The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Iwahana H., Biochem. Biophys. Res. Commun. 219:249-255(1996). Davidson J.N., DNA Cell Biol. 9:667-676(1990). Olsen J.V., Cell 127:635-648(2006).
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around phosphorylation site of threonine 456 (P-I-T(p)-P-H) derived from Human CAD.
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:Phospho-CAD-Thr456-Antibody-11084239.html
