ARHGEF1 Antibody
Produktgrößen
100 ul
£332,00
CSB-PA791509-100UL
Über dieses Produkt
- SKU:
- CSB-PA791509
- Zusätzliche Namen:
- 115 kD protein antibody; 115 kDa guanine nucleotide exchange factor antibody; ARHG1_HUMAN antibody; ARHGEF 1 antibody; ARHGEF1 antibody; GEF 1 antibody; GEF1 antibody; LBCL 2 antibody; LBCL2 antibody; LSC antibody; Lsc homolog antibody; p115 RhoGEF antibody; p115-RhoGEF antibody; p115RhoGEF antibody; Rho guanine nucleotide exchange factor (GEF) 1 antibody; Rho guanine nucleotide exchange factor 1 antibody; Sub1.5 antibody
- Anwendung:
- ELISA, Western Blot
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Klonalität:
- Polyclonal
- Weitere Details:
- Seems to play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13) subunits. Acts as GTPase-activating protein (GAP) for GNA12 and GNA13, and as guanine nucleotide exchange factor (GEF) for RhoA GTPase. Activated G alpha 13/GNA13 stimulates the RhoGEF activity through interaction with the RGS-like domain. This GEF activity is inhibited by binding to activated GNA12. Mediates angiotensin-2-induced RhoA activation. Farmer A., Submitted (MAY-2003). Wedegaertner P.B., J. Biol. Chem. 275:14992-14999(2000). Han D.K., Sci. Signal. 2:RA46-RA46(2009).
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from internal of Human ARHGEF1.
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:ARHGEF1-Antibody-11086203.html
