MRPS12 Antibody
Produktgrößen
100 ul
£332,00
CSB-PA788592-100UL
Über dieses Produkt
- SKU:
- CSB-PA788592
- Zusätzliche Namen:
- 28S ribosomal protein S12 antibody; 28S ribosomal protein S12 mitochondrial antibody; mitochondrial antibody; Mitochondrial ribosomal protein S12 antibody; MRP-S12 antibody; MRPS12 antibody; MT-RPS12 antibody; RPMS12 antibody; RPS12 antibody; RPSM12 antibody; RT12_HUMAN antibody; S12mt antibody
- Anwendung:
- ELISA, Western Blot
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Klonalität:
- Polyclonal
- Weitere Details:
- Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S12P family. The encoded protein is a key component of the ribosomal small subunit and controls the decoding fidelity and susceptibility to aminoglycoside antibiotics. The gene for mitochondrial seryl-tRNA synthetase is located upstream and adjacent to this gene, and both genes are possible candidates for the autosomal dominant deafness gene (DFNA4). Splice variants that differ in the 5' UTR have been found for this gene; all three variants encode the same protein. Shah Z.H., Gene 204:55-62(1997). Johnson D.F., Genomics 52:363-368(1998). Ebert L., Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases.
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from internal of Human MRPS12.
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:MRPS12-Antibody-11085505.html
