MOB1B Antibody
Produktgrößen
50 ul
£186,00
CSB-PA788447-50UL
100 ul
£334,00
CSB-PA788447-100UL
Über dieses Produkt
- SKU:
- CSB-PA788447
- Zusätzliche Namen:
- MATS 2 antibody; MATS2 antibody; MGC33910 antibody; Mob 1A antibody; Mob 1B antibody; MOB 4A antibody; MOB kinase activator 1B antibody; Mob1 homolog 1A antibody; MOB1 Mps One Binder homolog B antibody; MOB1 Mps one binder kinase activator like 1A antibody; Mob1A antibody; Mob1B antibody; MOBKL 1A antibody; MOBKL1A antibody; MOL1A_HUMAN antibody; Mps one binder kinase activator like 1A antibody; Mps one binder kinase activator-like 1A antibody; Protein Mob4A antibody
- Anwendung:
- ELISA, Western Blot
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Weitere Details:
- The protein encoded by this gene is similar to the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation. Three transcript variants encoding different isoforms have been found for this gene. Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of Human MOB1B
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:MOB1B-Antibody-11103669.html
