CAB39 Antibody
Produktgrößen
50 ul
£186,00
CSB-PA782755-50UL
100 ul
£334,00
CSB-PA782755-100UL
Über dieses Produkt
- SKU:
- CSB-PA782755
- Zusätzliche Namen:
- Cab39 antibody; CAB39_HUMAN antibody; Calcium binding protein 39 antibody; Calcium-binding protein 39 antibody; CGI 66 antibody; CGI-66 antibody; CGI66 antibody; MO25 alpha antibody; MO25 antibody; Mouse protein 25 alpha antibody; Protein Mo25 antibody
- Anwendung:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Weitere Details:
- Peutz-Jeghers Syndrome (PJS) is a rare hereditary disease characterized by melanocytic macules of the lips, gastrointestinal hamartomatous polyps and an increased risk for many classes of cancer. The serine/threonine kinase LKB1 (also designated STK11) has been identified as the gene mutated in PJS. LKB1 activity increases upon the binding of a regulatory complex consisting of the STE20-related adaptor-alpha (STRAD alpha) pseudo kinase and the calcium binding protein 39 (MO25 alpha). STRAD and MO25 determine the subcellular localization of LKB1 by initiating its translocation from the nucleus to the cytoplasm, thus regulating the tumor suppressor activity of LKB1. The LKB1/STRAD/MO25 complex acts as an AMP-activated protein kinase kinase (AMPKK).
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of Human CAB39
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:CAB39-Antibody-11105091.html
