PTPN22 Antibody
Produktgrößen
100 ul
£332,00
CSB-PA780242-100UL
Über dieses Produkt
- SKU:
- CSB-PA780242
- Zusätzliche Namen:
- Hematopoietic cell protein tyrosine phosphatase 70Z PEP antibody; Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP antibody; Lymphoid phosphatase antibody; Lymphoid specific protein tyrosine phosphatase antibody; lymphoid-specific; inducible human protein tyrosine phosphatase antibody; Lyp 1 antibody; Lyp 2 antibody; LyP antibody; Lyp1 antibody; Lyp2 antibody; LyPTP antibody; OTTHUMP00000013720 antibody; OTTHUMP00000013721 antibody; OTTHUMP00000233450 antibody; OTTHUMP00000233451 antibody; PEP antibody; PEST-domain phosphatase antibody; Protein tyrosine phosphatase non receptor type 22 (lymphoid) antibody; Protein tyrosine phosphatase non receptor type 22 antibody; Protein tyrosine phosphatase non receptor type 8 antibody; Protein tyrosine phosphatase non receptor type 8; formerly antibody; PTN22_HUMAN antibody; PTPN 22 antibody; PTPN 8 antibody; Ptpn22 antibody; PTPN8 antibody; PTPN8; formerly antibody; Tyrosine-protein phosphatase non-receptor type 22 antibody
- Anwendung:
- ELISA, Western Blot
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Klonalität:
- Polyclonal
- Weitere Details:
- Acts as negative regulator of T-cell receptor (TCR) signaling by direct dephosphorylation of the Src family kinases LCK and FYN, ITAMs of the TCRz/CD3 complex, as well as ZAP70, VAV, VCP and other key signaling molecules. Associates with and probably dephosphorylates CBL. Dephosphorylates LCK at its activating 'Tyr-394' residue. Dephosphorylates ZAP70 at its activating 'Tyr-493' residue. Dephosphorylates the immune system activator SKAP2. Cohen S., Blood 93:2013-2024(1999). Liu T., Submitted (JUL-1998) to the EMBL/GenBank/DDBJ databases. Wang S., Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases.
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from Internal of Human PTPN22.
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:PTPN22-Antibody-11086327.html
