PIM3 Antibody
Produktgrößen
50 ug
£186,00
CSB-PA771444LA01HU-50UG
100 ug
£334,00
CSB-PA771444LA01HU-100UG
Über dieses Produkt
- SKU:
- CSB-PA771444LA01HU
- Zusätzliche Namen:
- Kid 1 antibody; Kid1 antibody; Kinase induced by depolarization antibody; ONCOGENE PIM3 antibody; PIM 3 antibody; Pim 3 oncogene antibody; Pim-3 proto-oncogene; serine/threonine kinase antibody; PIM3 antibody; Pim3 oncogene antibody; PIM3_HUMAN antibody; Protein kinase Kid 1 antibody; Protein kinase Kid1 antibody; Serine/threonine kinase Pim 3 antibody; Serine/threonine kinase Pim3 antibody; Serine/threonine protein kinase Pim 3 antibody; Serine/threonine protein kinase Pim3 antibody; Serine/threonine-protein kinase Pim-3 antibody
- Anwendung:
- ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Klonalität:
- Polyclonal
- Weitere Details:
- Proto-oncogene with serine/threonine kinase activity that can prevent apoptosis, promote cell survival and protein translation. May contribute to tumorigenesis through: the delivery of survival signaling through phosphorylation of BAD which induces release of the anti-apoptotic protein Bcl-X(L), the regulation of cell cycle progression, protein synthesis and by regulation of MYC transcriptional activity. Additionally to this role on tumorigenesis, can also negatively regulate insulin secretion by inhibiting the activation of MAPK1/3 (ERK1/2), through SOCS6. Involved also in the control of energy metabolism and regulation of AMPK activity in modulating MYC and PPARGC1A protein levels and cell growth.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Serine/threonine-protein kinase pim-3 protein (278-326AA)
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:PIM3-Antibody-12549349.html
