CRTC1 Antibody
Produktgrößen
50 ug
£186,00
CSB-PA757785LA01HU-50UG
100 ug
£334,00
CSB-PA757785LA01HU-100UG
Über dieses Produkt
- SKU:
- CSB-PA757785LA01HU
- Zusätzliche Namen:
- KIAA0616 antibody; CREB regulated transcription coactivator 1 antibody; CREB-regulated transcription coactivator 1 antibody; CRTC1 antibody; CRTC1_HUMAN antibody; FLJ14027 antibody; MECT 1 antibody; Mucoepidermoid carcinoma translocated 1 antibody; Mucoepidermoid carcinoma translocated protein 1 antibody; TORC-1 antibody; TORC1 antibody; Transducer of CREB protein 1 antibody; Transducer of regulated cAMP response element binding protein 1 antibody; Transducer of regulated cAMP response element-binding protein (CREB) 1 antibody; Transducer of regulated cAMP response element-binding protein 1 antibody; WAMTP1 antibody
- Anwendung:
- ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
- Klonalität:
- Polyclonal
- Weitere Details:
- Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR). In the hippocampus, involved in late-phase long-term potentiation (L-LTP) maintenance at the Schaffer collateral-CA1 synapses. May be required for dendritic growth of developing cortical neurons (By similarity). In concert with SIK1, regulates the light-induced entrainment of the circadian clock. In response to light stimulus, coactivates the CREB-mediated transcription of PER1 which plays an important role in the photic entrainment of the circadian clock.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human CREB-regulated transcription coactivator 1 protein (1-248AA)
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:CRTC1-Antibody-12552555.html
