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Antikörper

KCNJ11 Antibody

Produktgrößen
50 ul
£186,00
CSB-PA746124-50UL
100 ul
£334,00
CSB-PA746124-100UL
Über dieses Produkt
SKU:
CSB-PA746124
Zusätzliche Namen:
KCNJ11 antibody; ATP-sensitive inward rectifier potassium channel 11 antibody; IKATP antibody; Inward rectifier K(+) channel Kir6.2 antibody; Potassium channel antibody; inwardly rectifying subfamily J member 11 antibody
Anwendung:
ELISA, Immunohistochemistry
Buffer:
PBS
Klonalität:
Polyclonal
Weitere Details:
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and is found associated with the sulfonylurea receptor SUR. Mutations in this gene are a cause of familial persistent hyperinsulinemic hypoglycemia of infancy (PHHI), an autosomal recessive disorder characterized by unregulated insulin secretion. Defects in this gene may also contribute to autosomal dominant non-insulin-dependent diabetes mellitus type II (NIDDM), transient neonatal diabetes mellitus type 3 (TNDM3), and permanent neonatal diabetes mellitus (PNDM). Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
Host:
Rabbit
Immunogen:
Fusion protein of Human KCNJ11
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody