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Antikörper

ATG1 Antibody, FITC conjugated

Produktgrößen
50 ug
£186,00
CSB-PA738902LC01CZI-50UG
100 ug
£334,00
CSB-PA738902LC01CZI-100UG
Über dieses Produkt
SKU:
CSB-PA738902LC01CZI
Zusätzliche Namen:
ATG1 antibody; CAGL0L06006g antibody; Serine/threonine-protein kinase ATG1 antibody; EC 2.7.11.1 antibody; Autophagy-related protein 1 antibody
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Klonalität:
Polyclonal
Konjugat:
FITC
Weitere Details:
Serine/threonine protein kinase involved in the cytoplasm to vacuole transport (Cvt) and found to be essential in autophagy, where it is required for the formation of autophagosomes. Involved in the clearance of protein aggregates which cannot be efficiently cleared by the proteasome. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Also involved in endoplasmic reticulum-specific autophagic process, in selective removal of ER-associated degradation (ERAD) substrates. Plays a key role in ATG9 and ATG23 cycling through the pre-autophagosomal structure and is necessary to promote ATG18 binding to ATG9 through phosphorylation of ATG9.
Host:
Rabbit
Immunogen:
Recombinant Candida glabrata Serine/threonine-protein kinase ATG1 protein (11-312AA)
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Protein G Purified
Reaktivitäten:
Yeast/Fungi
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody