LDLRAP1 Antibody
Produktgrößen
50 ul
£186,00
CSB-PA729190ESR2HU-50UL
100 ul
£334,00
CSB-PA729190ESR2HU-100UL
Über dieses Produkt
- SKU:
- CSB-PA729190ESR2HU
- Zusätzliche Namen:
- ARH antibody; ARH GENE antibody; ARH_HUMAN antibody; ARH1 antibody; ARH2 antibody; Autosomal recessive hypercholesterolemia protein antibody; DKFZp586D0624 antibody; FHCB1 antibody; FHCB2 antibody; LDL receptor adaptor protein antibody; Ldlrap1 antibody; Low density lipoprotein receptor adapter protein 1 antibody; MGC34705 antibody; OTTHUMP00000008526 antibody
- Anwendung:
- ELISA, Immunohistochemistry
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Weitere Details:
- Adapter protein (clathrin-associated sorting protein (CLASP)) required for efficient endocytosis of the LDL receptor (LDLR) in polarized cells such as hepatocytes and lymphocytes, but not in non-polarized cells (fibroblasts). May be required for LDL binding and internalization but not for receptor clustering in coated pits. May facilitate the endocytocis of LDLR and LDLR-LDL complexes from coated pits by stabilizing the interaction between the receptor and the structural components of the pits. May also be involved in the internalization of other LDLR family members. Binds to phosphoinositides, which regulate clathrin bud assembly at the cell surface.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Low density lipoprotein receptor adapter protein 1 protein (59-308AA)
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:LDLRAP1-Antibody-1091932.html
