LRRK2 Antibody
Produktgrößen
50 ug
£186,00
CSB-PA722493LA01HU-50UG
100 ug
£334,00
CSB-PA722493LA01HU-100UG
Über dieses Produkt
- SKU:
- CSB-PA722493LA01HU
- Zusätzliche Namen:
- augmented in rheumatoid arthritis 17 antibody; AURA17 antibody; Dardarin antibody; Leucine rich repeat kinase 2 antibody; leucine rich repeat serine threonine protein kinase 2 antibody; Leucine-rich repeat serine/threonine-protein kinase 2 antibody; LRRK 2 antibody; LRRK2 antibody; LRRK2_HUMAN antibody; PARK 8 antibody; PARK8 antibody; RIPK7 antibody; ROCO 2 antibody; ROCO2 antibody
- Anwendung:
- ELISA, Immunofluorescence, Immunohistochemistry
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
- Klonalität:
- Polyclonal
- Weitere Details:
- Positively regulates autophagy through a calcium-dependent activation of the CaMKK/AMPK signaling pathway. The process involves activation of nicotinic acid adenine dinucleotide phosphate (NAADP) receptors, increase in lysosomal pH, and calcium release from lysosomes. Together with RAB29, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner. Regulates neuronal process morphology in the intact central nervous system (CNS). Plays a role in synaptic vesicle trafficking. Phosphorylates PRDX3. Has GTPase activity. May play a role in the phosphorylation of proteins central to Parkinson disease.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Leucine-rich repeat serine/threonine-protein kinase 2 protein (2029-2275AA)
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:LRRK2-Antibody-12781360.html
