OAS1 Antibody
Produktgrößen
50 ug
£186,00
CSB-PA640913LA01HU-50UG
100 ug
£334,00
CSB-PA640913LA01HU-100UG
Über dieses Produkt
- SKU:
- CSB-PA640913LA01HU
- Zusätzliche Namen:
- (2 5')oligo(A) synthetase 1 antibody; (2-5'')oligo(A) synthase 1 antibody; 2 5 Oligoadenylate Synthetase 1 antibody; 2 5' oligo A synthase 1 antibody; 2 5' oligo A synthetase 1 antibody; 2 5A synthase 1 antibody; 2 5A synthetase 1 antibody; 2' 5' oligo A synthetase 1 antibody; 2' 5' oligoadenylate synthetase 1 40/46kDa antibody; 2' 5' oligoadenylate synthetase 1 antibody; 2' 5' oligoisoadenylate synthetase 1 antibody; 2''-5''-oligoadenylate synthase 1 antibody; 2'5' oligo A synthetase 1 antibody; 2'5' oligoadenylate synthetase 1 antibody; 2'5' oligoisoadenylate synthetase 1 antibody; 2-5A synthase 1 antibody; E18/E16 antibody; IFI 4 antibody; IFI4 antibody; OAS 1 antibody; OAS1 antibody; OAS1_HUMAN antibody; OIAS antibody; OIASI antibody; p46/p42 OAS antibody
- Anwendung:
- ELISA, Immunohistochemistry
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
- Klonalität:
- Polyclonal
- Weitere Details:
- Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes higher oligomers of 2'-5'-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition of protein synthesis, thus terminating viral replication. Can mediate the antiviral effect via the classical RNase L-dependent pathway or an alternative antiviral pathway independent of RNase L. The secreted form displays antiviral effect against vesicular stomatitis virus (VSV), herpes simplex virus type 2 (HSV-2), and encephalomyocarditis virus (EMCV) and stimulates the alternative antiviral pathway independent of RNase L.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human 2\'-5\'-oligoadenylate synthase 1 protein (296-395AA)
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:OAS1-Antibody-12554390.html
