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Antikörper

PLCL1 Antibody

Produktgrößen
50 ug
£186,00
CSB-PA624015LA01HU-50UG
100 ug
£334,00
CSB-PA624015LA01HU-100UG
Über dieses Produkt
SKU:
CSB-PA624015LA01HU
Zusätzliche Namen:
Inactive phospholipase C-like protein 1 antibody; Inactive protein 1 antibody; Phospholipase C deleted in lung carcinoma antibody; Phospholipase C epsilon antibody; Phospholipase C like 1 antibody; Phospholipase C related but catalytically inactive protein antibody; Phospholipase C related, but catalytically inactive protein antibody; Phospholipase C-deleted in lung carcinoma antibody; Phospholipase C-related but catalytically inactive protein antibody; Phospholipase C-related catalytically antibody; PLC-L1 antibody; PLCE antibody; PLCL antibody; PLCL1 antibody; PLCL1_HUMAN antibody; PLDL1 antibody; PRIP antibody
Anwendung:
ELISA, Immunofluorescence, Immunohistochemistry
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Klonalität:
Polyclonal
Weitere Details:
Involved in an inositol phospholipid-based intracellular signaling cascade. Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol. Component in the phospho-dependent endocytosis process of GABA A receptor (By similarity). Regulates the turnover of receptors and thus contributes to the maintenance of GABA-mediated synaptic inhibition. Its aberrant expression could contribute to the genesis and progression of lung carcinoma. Acts as an inhibitor of PPP1C.
Host:
Rabbit
Immunogen:
Recombinant Human Inactive phospholipase C-like protein 1 protein (1-108AA)
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Protein G Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody
Immunofluorescence staining of A549 cells with CSB-PA624015LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
IHC image of CSB-PA624015LA01HU diluted at 1:300 and staining in paraffin-embedded human heart tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
IHC image of CSB-PA624015LA01HU diluted at 1:300 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.