LRRC32 Antibody
Produktgrößen
50 ug
£186,00
CSB-PA618886LA01HU-50UG
100 ug
£334,00
CSB-PA618886LA01HU-100UG
Über dieses Produkt
- SKU:
- CSB-PA618886LA01HU
- Zusätzliche Namen:
- D11S833E antibody; GARP antibody; Garpin antibody; Glycoprotein A repetitions predominant antibody; Leucine rich repeat containing 32 antibody; Leucine-rich repeat-containing protein 32 antibody; LRC32_HUMAN antibody; LRRC32 antibody
- Anwendung:
- ELISA, Immunohistochemistry
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Klonalität:
- Polyclonal
- Weitere Details:
- Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space (PubMed:19750484, PubMed:19651619, PubMed:22278742). Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta (PubMed:22278742). Able to outcompete LTBP1 for binding to LAP regulatory chain of TGF-beta (PubMed:22278742). Controls activation of TGF-beta-1 (TGFB1) on the surface of activated regulatory T-cells (Tregs) (PubMed:19750484, PubMed:19651619). Required for epithelial fusion during palate development by regulating activation of TGF-beta-3 (TGFB3) (By similarity).
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Transforming growth factor beta activator LRRC32 protein (301-500AA)
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:LRRC32-Antibody-11113469.html
