HNRNPD Antibody
Produktgrößen
50 ul
£186,00
CSB-PA618874DSR1HU-50UL
100 ul
£334,00
CSB-PA618874DSR1HU-100UL
Über dieses Produkt
- SKU:
- CSB-PA618874DSR1HU
- Zusätzliche Namen:
- ARE binding protein AUFI type A antibody; AU-rich element RNA-binding protein 1 antibody; AUF antibody; AUF1 antibody; AUF1A antibody; Heterogeneous nuclear ribonucleoprotein D0 antibody; hnRNP D antibody; hnRNP D0 antibody; Hnrnpd antibody; hnRNPD0 antibody; HNRPD antibody; HNRPD_HUMAN antibody; P37 antibody
- Anwendung:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Weitere Details:
- Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3'-UTR of many proto-oncogenes and cytokine mRNAs. Also binds to double- and single-stranded DNA sequences in a specific manner and functions a transcription factor. Each of the RNA-binding domains specifically can bind solely to a single-stranded non-monotonous 5'-UUAG-3' sequence and also weaker to the single-stranded 5'-TTAGGG-3' telomeric DNA repeat. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats. Binding of RRM1 to DNA inhibits the formation of DNA quadruplex structure which may play a role in telomere elongation. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. May play a role in the regulation of the rhythmic expression of circadian clock core genes. Directly binds to the 3'UTR of CRY1 mRNA and induces CRY1 rhythmic translation. May also be involved in the regulation of PER2 translation.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Heterogeneous nuclear ribonucleoprotein D0 protein (1-306AA)
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:HNRNPD-Antibody-1091032.html
