NR3C1 (Ab-226) Antibody
Produktgrößen
100 ul
£332,00
CSB-PA589113-100UL
Über dieses Produkt
- SKU:
- CSB-PA589113
- Zusätzliche Namen:
- GCCR antibody; GCR antibody; GCR_HUMAN antibody; GCRST antibody; glucocorticoid nuclear receptor variant 1 antibody; Glucocorticoid receptor antibody; GR antibody; GRL antibody; Grl1 antibody; nr3c1 antibody; Nuclear receptor subfamily 3 group C member 1 antibody; nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) antibody
- Anwendung:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Klonalität:
- Polyclonal
- Weitere Details:
- Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodeling. May play a negative role in adipogenesis through the regulation of lipolytic and antilipogenic genes expression. Kyung Jin Kwak, J. Exp. Bot., Nov 2005; 56: 3007 - 3016. Maite de Llanos, Hum. Reprod., Jan 2005; 20: 216 - 220. M. Lynch, Mol. Hum. Reprod., Jul 2005; 11: 507 - 512. Valeriya P. Makarenkova, J. Immunol., Feb 2006; 176: 2085 - 2094.
- Host:
- Rabbit
- Immunogen:
- Synthesized non-phosphopeptide derived from Human GR around the phosphorylation site of serine 226/234/246 (L-L-S-P-L).
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:NR3C1-Ab-226-Antibody-11084314.html
