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Antikörper

HSP90AB1 (Ab-254) Antibody

Produktgrößen
100 ul
£332,00
CSB-PA575867-100UL
Über dieses Produkt
SKU:
CSB-PA575867
Zusätzliche Namen:
90 kda heat shock protein beta HSP90 beta antibody; D6S182 antibody; FLJ26984 antibody; Heat shock 84 kDa antibody; Heat shock 90kD protein 1; beta antibody; Heat shock 90kDa protein 1 beta antibody; Heat shock protein 90 alpha family class B member 1 antibody; Heat shock protein 90 kDa antibody; Heat shock protein 90kDa alpha (cytosolic) class B member 1 antibody; Heat shock protein 90kDa alpha family class B member 1 antibody; Heat shock protein beta antibody; Heat shock protein HSP 90 beta antibody; Heat shock protein HSP 90-beta antibody; HS90B_HUMAN antibody; HSP 84 antibody; HSP 90 antibody; HSP 90 b antibody; HSP 90b antibody; HSP84 antibody; HSP90 BETA antibody; hsp90ab1 antibody; HSP90B antibody; HSPC2 antibody; HSPCB antibody
Anwendung:
ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
phosphate buffered saline (without mg2+ and ca2+)
Klonalität:
Polyclonal
Weitere Details:
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Lothar Goretzki, AACR Meeting Abstracts, Apr 2006; 2006: 468. Jean-Fran?ois Louvion, Mol. Biol. Cell, Nov 1998; 9: 3071. Angelika Lueking, Mol. Cell. Proteomics, Dec 2003; 2: 1342. Jason Fontana Circ, Res., May 2002; 90: 866.
Host:
Rabbit
Immunogen:
Synthesized non-phosphopeptide derived from Human HSP90B around the phosphorylation site of serine 254 (V-G-S(p)-D-E).
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody
Immunofluorescence analysis of HeLa cells, treated with TNF-a (20nM, 15mins), using HSP90B (Ab-254) antibody.
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using HSP90B (Ab-254) antibody.
Western blot analysis of extracts from Hela cells treated with TNF-A Alpha (20ng/ml, 30min), using HSP90B (Ab-254) antibody.
Western blot analysis of extracts from HeLa cells (Lane 2), CoLo cells (Lane 3), HepG2 cells (Lane 4) and 293 cells (Lane 5), using HSP90B (Ab-254) antiobdy. The lane on the left is treated with synthesized peptide.