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Antikörper

KRT17 Antibody

Produktgrößen
100 ul
£332,00
CSB-PA442800-100UL
Über dieses Produkt
SKU:
CSB-PA442800
Zusätzliche Namen:
39.1 antibody; CK 17 antibody; CK-17 antibody; Cytokeratin-17 antibody; K17 antibody; K1C17_HUMAN antibody; Keratin 17 antibody; keratin 17 epitope S1 antibody; keratin 17 epitope S2 antibody; keratin 17 epitope S4 antibody; Keratin 17, type I antibody; Keratin antibody; Keratin type I cytoskeletal 17 antibody; keratin, type i cytoskeletal 17 [version 1] antibody; Keratin-17 antibody; KRT17 antibody; PC antibody; PC2 antibody; PCHC1 antibody; type I cytoskeletal 17 antibody
Anwendung:
ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
phosphate buffered saline (without mg2+ and ca2+)
Klonalität:
Polyclonal
Weitere Details:
May play a role in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair. May be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial stem cells". May act as an autoantigen in the immunopathogenesis of psoriasis, with certain peptide regions being a major target for autoreactive T-cells and hence causing their proliferation. Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state. Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway. Involved in tissue repair By similarity. M Rosenberg, Mol. Cell. Biol., Feb 1988; 8: 722 - 736. SM Troyanovsky, J. Cell Sci., Jul 1989; 93: 419. Kevin M. McGowan, Genes & Dev., Jun 2002; 16: 1412. Nicholas Bianchi, Mol. Cell. Biol., Aug 2005; 25: 7249 - 7259."
Host:
Rabbit
Immunogen:
Synthesized peptide derived from Human keratin 17.
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody